The Joshi lab is looking for a highly motivated postdoc to work on an exciting project at the intersection between cancer biology and immunology in pancreatic cancer. The goals of this project is to use mouse and human pancreatic cancer organoid models to investigate the immune response to pancreatic cancer and the role of the protein Renalase for tumor growth. Renalase is a novel therapeutic target in pancreatic and other cancers and the project will focus on the immune and stromal sources of Renalase in the tumor microenvironment, and their importance for tumor growth.
The person hired for this position will join a team of basic laboratory researchers and clinicians in this effort and will participate in the generation of organoids from biopsy samples from pancreatic cancer patients. This person will also perform in vitro and in vivo experiments to analyze the organoids and interactions with immune and stromal cells.
Requirements: A top-tier Ph.D. in cell biology, cancer biology, or immunology. Experience working with organoid models preferred, but not required. Must have excellent oral and written communication skills and the ability to perform both self-directed and guided research. Must also have strong personal initiative and the ability to work effectively as part of a team. Ability to meet deadlines and efficiently multitask is a must.
Interested individuals should email nikhil.joshi at yale.edu and include CV and references.