This position is responsible for designing and performing Pharmacology studies in immunology/immuno-oncology to support broad scope of drug development programs. Candidate must possess strong immunology/immuno-oncology pharmacology experience with drug development focus. Ideal candidate will have broad knowledge of, and laboratory experience with: immune cell functional and mechanistic assays, tumor cell lines appropriate for interrogating immune-mediated oncology therapies, syngeneic animal models, PDX and/or humanized mouse models; be able to act independently and collaboratively, with the potential to take on additional responsibility, including project team leadership and managing direct reports. Reports to the Associate Director, Pharmacology and Toxicology
This scientist will conduct routine research in pharmacology to support Array Discovery Research and Exploratory Development projects. Standard in vivo and in vitro pharmacology testing skills are required. These skills include but are not limited to: animal handling and restraint, compound dosing, inoculation, blood and tissue sampling, small animal surgical techniques, necropsy procedures, physiological monitoring, efficacy and pharmacodynamic assessments in various small animal models of human disease, cell culture and basic wet-lab techniques (e.g., western blotting, FACS). Experience in designing and performing a variety efficacy and pharmacodynamic studies, data collection, analysis and interpretation are required. Computer skills with MS Office/Excel are required. Candidates should possess excellent communication skills and the ability to multi-task in a fast-paced environment.
Skills & Requirements
- PhD with 8+ years post-doctoral experince with at least 3 years in the pharmaceutical industry.
- Extensive immunology/immuno-oncology expertise as evidenced by strong publication, funded grant and/or patent records is required
- Demonstrated ability to work independently
- Ability to communicate effectively, both written and oral